Nitric Oxide + Iodine Delivery Platform
Nitric Oxide + Iodine · Delivery Platform

Reimagining Nasal
Antimicrobial Defence

A next-generation intranasal delivery platform combining dual antimicrobial mechanisms with sustained mucosal protection—engineered for real-world clinical use.

From rapid pathogen inactivation to prolonged protection, this platform expands beyond single-agent limitations to enable broader, more durable respiratory defence.

Current intranasal therapies are
short-acting and narrowly targeted

Most currently available nasal antimicrobial products rely on single active mechanisms and provide only transient protection. While effective in specific use cases, they face fundamental limitations:

Short duration of action requiring frequent dosing
Narrow spectrum — primarily antiviral
Limited applicability beyond pandemic-driven indications
Reduced effectiveness in complex, polymicrobial environments

This has resulted in underutilisation outside acute scenarios and limited long-term clinical relevance.

A broader need: sustained,
multi-pathogen mucosal protection

Upper respiratory environments are exposed to viral, bacterial, and fungal pathogens simultaneously. Yet, no current solution delivers all three requirements:

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Sustained antimicrobial presence at the mucosal surface

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Broad-spectrum pathogen coverage — viral, bacterial, and fungal

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Safe, repeatable use in chronic or preventive settings

This gap represents a significant opportunity to move from episodic treatment → continuous protection.

A dual-mechanism
antimicrobial delivery platform

Our platform is built on the co-liberation of two complementary antimicrobial agents, delivered through a controlled-release intranasal system.

Nitric Oxide

NO — Rapid reactive action

  • Immediate pathogen reduction
  • Damages microbial DNA and cellular structures
  • Breaks down biofilms
  • Enhances innate immune response

Molecular Iodine

I₂ — Persistent broad-spectrum control

  • Sustained antimicrobial activity
  • Effective across bacteria, fungi, and viruses
  • Low resistance potential
  • Proven antimicrobial agent in clinical settings
Synergistic Effect →
Immediate + sustained activity Multi-pathogen coverage Reduced resistance likelihood Enhanced complex infection control

Complementary mechanisms.
Amplified effect.

Each agent contributes a distinct and validated mode of antimicrobial action. Together, they address the full spectrum of mucosal defence requirements.

Nitric Oxide (NO)

  • Disrupts viral replication cycles
  • Damages microbial DNA and cellular structures
  • Breaks down biofilms
  • Enhances innate immune response

Molecular Iodine (I₂)

  • Rapid oxidation of microbial proteins and lipids
  • Effective across bacteria, fungi, and viruses
  • Low resistance potential
  • Proven antimicrobial agent in clinical settings

Duration defines
effectiveness

Traditional nasal sprays act quickly—but dissipate rapidly. Our platform introduces controlled release kinetics enabling meaningful, prolonged mucosal defence.

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Prolonged Residence

Extended mucosal residence time beyond conventional sprays

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Reduced Dosing

Lower dosing frequency without compromising coverage

Better Compliance

Improved patient adherence through simpler regimens

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Continuous Cover

Uninterrupted antimicrobial activity at the mucosal interface

🏥 High-risk environments 🫁 Chronic respiratory conditions 🩺 Preventive healthcare settings

Designed for real-world respiratory care

The platform is adaptable across multiple clinical contexts. Unlike single-indication products, this platform supports broad, longitudinal use cases.

Upper respiratory tract infections (URTIs)

Rhinitis and sinusitis

Post-operative infection prevention

Immunocompromised patient protection

Fungal and polymicrobial colonisation

Beyond single-agent
nasal therapies

Single-agent products have struggled with narrow scope and short lifecycle, highlighting the need for a more evolved approach.

Dimension Conventional NO Spray This Platform
Mechanism Single agent (NO only) Dual mechanism (NO + Iodine)
Duration Short-lived Sustained release
Spectrum Primarily antiviral Antiviral + antibacterial + antifungal
Use Case Pandemic-specific Broad clinical + preventive
Lifecycle Limited Long-term clinical relevance

From molecule to mucosa—
engineered performance

This is not a formulation — it is a delivery platform. It represents a foundation for a new class of intranasal antimicrobial solutions.

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Enable co-delivery of complementary active agents within a single system

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Control release kinetics precisely at the mucosal interface

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Support scalable manufacturing and adaptation across formats

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Extend into multiple therapeutic indications beyond initial use

Expanding demand for non-invasive
antimicrobial solutions

Global and Indian markets are witnessing a convergence of trends that position this platform at a critical inflection point.

Rising respiratory disease burden globally

Shift toward preventive and proactive healthcare

Increased adoption of non-invasive delivery systems

Demand for OTC and accessible antimicrobial solutions

Platform positioned at the intersection of

🦠 Infectious Disease 👂 ENT & Respiratory Care 🩺 Preventive Healthcare 💊 Drug Delivery Innovation

Built for partnerships and scale

The platform enables faster translation from concept to clinic, while maintaining flexibility across indications and partner requirements.

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Integration into existing respiratory portfolios

Rapid clinical advancement pathways

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Scalable manufacturing and commercialisation

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Strategic collaboration with pharmaceutical partners

Advance the next generation of
antimicrobial delivery

Explore how this platform can support your respiratory, infectious disease, and preventive care pipeline.

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